Siberian Federal University 
- Issue
- Journal of Siberian Federal University. Biology. 2026 19 (2)
- Authors
- Kiselev, Evgeniy G.
- Contact information
- Kiselev, Evgeniy G. : Institute of Biophysics SB RAS Federal Research Center “Krasnoyarsk Science Center SB RAS” (Krasnoyarsk, Russian Federation Siberian); Federal University (Krasnoyarsk, Russian Federation); ; ORCID: 0000-0003-4472-7087
- Keywords
- degradable polyhydroxyalkanoates; biosynthesis; various carbon substrates; pilot production; production parameters; carbon substrate consumption efficiency
- Abstract
The study describes investigation and implementation of the synthesis of degradable bioplastics – polyhydroxyalkanoates (PHAs), which was scaled up to conditions of pilot production in a 150-liter fermenter. Sugar-containing hydrolysates of Jerusalem artichoke tubers, purified and crude glycerol, and two types of fatty waste from fish processing (Baltic sprat and Atlantic mackerel) were studied as the sole carbon substrates, compared with fructose and glucose. High PHA yields (75±5 %) were obtained on all substrates, with varying productivity and C‑substrate efficiency. The highest total biomass and polymer yields, 3.7–3.8 and 3.2–3.5 g/L∙h, respectively, were produced using two sources of fish processing fat, with the highest yield coefficients (0.62–0.66 and 0.57–0.59 g/g), which exceeded the outcomes from all other substrates by 1.5 to 2.0 times. The results of PHA synthesis are superior to all known data obtained using glycerol and fish processing fat waste and form the basis for the development of Initial data and scaling up the technology to the pilot industrial level
- Pages
- 345–357
- EDN
- QDVXIE
- Paper at repository of SibFU
- https://elib.sfu-kras.ru/handle/2311/159251
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).